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Alzheimer's Association International Conference (AAIC) · 2024:Poster Tue-17 · Hendrix, Dickson et al.
Companies recently identified clinical study sites engaging in fraudulent practices, reducing success in Alzheimer's disease (AD) clinical trials. Successful trials are reliable…
When the sample size a conventional design demands is larger than the trial you can run, a Global Statistical Test lets the clinical-endpoint hypotheses be tested anyway. The paper sets out when GST applies, how it is pre-specified, and how it has been received in review.
4 publications
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2003 · Journal of Emotional Abuse
Abstract: This research explored whether witnessing spouse abuse influences children's use of violent and peaceful behavior in conflicts with peers. Sixty-two child witnesses were compared with 53 non-witnesses across five types of childhood conflicts: limited resources, exclusion, aggression, intimidation, and jealousy. Each conflict was presented in two formats: (1) hypothetical conflicts, and (2) simulated conflict situations. For both, most children, and particularly non-witness males, were consistently peaceful. However, male witnesses were inconsistent and violent in both conflict formats. Female witnesses proposed peaceful strategies in hypothetical conflicts, but were inconsistent and violent in simulated conflicts. Female non-witnesses were consistent and peaceful in simulated conflicts, but were inconsistent and more violent in hypothetical conflicts. Group differences wereprimarily due to subsets of children.
2003 · Patent
Brown, Bruce · Hendrix, Kent · Hendrix, Suzanne
Abstract: A Statistical Comparator Interface provides a user with the capability to reduce vast amounts of raw data into a readily navigable and quickly comprehendible form. The Statistical Comparator Interface is embodied in two basic stages. In a data compilation stage, a compilation module, which is preferably implemented with computer software, receives the raw data and compiles the raw data into a format that is readily navigable by a navigation engine. This may include expanding the data through statistical computations and arranging the data in a data matrix complete with hierarchal indices. In a navigation stage, the navigation engine is employed to allow a user to generate data profiles from among the formatted data, including selecting a peer group with selected characteristics and selecting statistical comparisons to be calculated and displayed for the selected peer group. The navigation stage may also allow the user to select from among a plurality of graphical depiction schemes to display the selected statistical comparisons in a manner that is readily comprehendible to a lay, unindoctrinated user. The graphical display schemes preferably employ multivariate statistical methods such as MANOVA, discriminate analysis, multivariate multiple regression, etc., and multivariate graphing methods such as three-dimensional scatter plots and ordered profile surfaces to display the highly complex data in a readily understandable format.
2003 · Theoretical psychology: critical contributions
Brown, Bruce · Hendrix, Suzanne
Summary: In answer to Robinson's trenchant critique of the inadequacies of multivariate statistical decision theory in psychology and the reification of factor structure be replaced with a new way of dealing with data, through structuralndescription and graphics, "visual parables" if you will. In keeping with this structural emphasis, following a brief discussion of notable failings of the traditional approach, a number of examples of descriptive multivariate graphics are given with explanation. Three kinds of data are illustrated: an analysis of paradoxical results in vocal expression of emotion, an experimental study of supercomputer performance data (as a mechanistic analogue to human performance measurement), and a canonical correlation analysis of the correspondence of mutual fund performance to market indices for use in studies of contextually informed market trading behaviour. Future directions and practical applications are discussed.
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